Dr. Rigobert Kefferputz

Patient Library / Toxicity & Detoxification / Mold & CIRS

Mold & CIRS

Chronic inflammatory response syndrome from mold exposure is one of the most underdiagnosed causes of complex, multi-system illness.

Mold-related illness — specifically Chronic Inflammatory Response Syndrome (CIRS) — affects roughly 25% of the population who carry specific HLA gene variants. These individuals cannot clear biotoxins from water-damaged buildings, leading to a dysregulated immune response that produces a bewildering array of multi-system symptoms. Most patients spend years being told nothing is wrong with them. Something is wrong — and it's identifiable.

Genetic Susceptibility

Only about 25% of people exposed to water-damaged buildings develop CIRS — those with specific HLA gene variants that impair biotoxin clearance. The other 75% aren't affected. This explains why not everyone in the same building gets sick.

Environmental Remediation First

No treatment produces lasting results while mold exposure continues. Environmental remediation and removal from the water-damaged space is the non-negotiable first step — without it, recovery is impossible.

A Staged Protocol Exists

The Shoemaker protocol provides a validated, sequential treatment framework for CIRS with specific lab markers to guide each stage of recovery. It works — but it takes 12–18 months and requires expert guidance.

What You Need to Know

Frequently Asked Questions

How I Treat This

These are the services I most commonly draw on when working with mold & cirs.

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