Patient Library / Infections / Long COVID

Long COVID

Long COVID affects millions and shares mechanisms with ME/CFS, understanding those mechanisms points toward real treatment options.

Long COVID affects an estimated 10–30% of people after COVID-19 infection and has become one of the most significant chronic disease burdens of the decade. It is not 'just fatigue after a virus'; it has measurable biological mechanisms including viral persistence, microclotting, MCAS, mitochondrial dysfunction, and autonomic dysregulation. These mechanisms are increasingly well-characterized and treatable.

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Multiple Mechanisms

Long COVID involves at least five distinct biological mechanisms: viral persistence, MCAS, microclotting, mitochondrial dysfunction, and autonomic dysregulation, which explains why symptoms vary so dramatically between individuals.

Pacing Is Non-Negotiable

For patients with post-exertional malaise, pushing through fatigue consistently causes worsening, sometimes permanent. Energy pacing is the most important foundational intervention before any other treatment is added.

Targeted Treatment Works

Nattokinase, LDN, antihistamines, mitochondrial support, and antiviral strategies each target specific long COVID mechanisms with growing evidence. Investigation-driven, individualized treatment produces significantly better outcomes than generic protocols.

What You Need to Know

Frequently Asked Questions

References & Further Reading

This article is for education and is not a substitute for individual medical advice. For background reading, these independent health authorities offer evidence-based information:

How I Treat This

These are the services I most commonly draw on when working with long covid.

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